Funding

Our research is generously supported by federal and nonfederal funders committed to generating foundational knowledge of the neurobiology of wellbeing and resilience.

Current support

Kellogg Foundation

COVID-19 Mother Baby Outcomes Initiative

The COVID-19 Mother Baby Outcomes (COMBO) Initiative monitors the health and wellbeing of children born during the pandemic with and without in utero exposure to maternal SARS-CoV-2 infection, as well as the health and wellbeing of their mothers. This grant will cover the costs of conducting 18-month and 24-month assessments on up to 450 already enrolled COMBO dyads.

Year:  2022-2024  /  Month:  January  /  Role: PI  /  Donation: $400,000  /   Dumitriu (PI)

NIH/NHLBI

NIH RECOVER: A multi-site observational study of post-acute sequelae of SARS-CoV-2 infection in pediatric populations

This study seeks to characterize the incidence and prevalence of sequelae of SARS-CoV-2 infection occurring >30 days after index infection; characterize the spectrum of clinical symptoms, subclinical organ dysfunction, natural history, and distinct phenotypes identified as sequelae of SARS-CoV-2 infection occurring >30 days after index infection; and define the biological mechanisms underlying pathogenesis of the sequelae of SARS-CoV-2 infection occurring >30 days after index infection.

Year:  2020-2025  /  Month:  September  /  Role: Other Significant Contributor  /  Donation: $9,404,396  /   Stockwell, Berman-Rosenzweig, Milne

NIH/NIMH

COVID-19 Mother Baby Outcomes (COMBO): brain-behavior functioning

COMBO seeks to understand the effects of COVID-19 on newborns born during the pandemic and their mothers. This proposal will investigate the socioemotional health of the mother-infant dyad.

Year:  2021-2026  /  Month: April /  Role: Contact PI /  Direct annual cost: $565,100  /  Dumitriu, Monk, Marsh (MPI)

Past support

NIH/NIMH

NIH RECOVER: A multi-site observational study of post-acute sequelae of SARS-CoV-2 infection in pediatric populations

Structural and Social Determinants of Maternal Mental Health, Morbidity, and Inequities in COMBO This NOSI NOT-OD-21-071 Administrative Supplement will expand the scope and focus of the parent R01 project beyond mother-infant brain-behavior functioning, focusing on structural racism and discrimination (SRD) in COMBO mothers.

Year:  2021-2022  /  Month: August  /  Role: Contact PI  /  Donation: $663,061  /   Dumitriu, Marsh, Monk (MPI)

CDC and Abt Associates

Epidemiology of SARS-CoV-2 in Pregnancy and Infancy (ESPI)

Epidemiology of SARS-CoV-2 in Pregnancy and Infancy COVID-19 Mother Baby Outcomes (ESPI COMBO) study.
This sub-study will follow up participants enrolled in CDC’s national surveillance project, ESPI, through 6 months of age to understand the long-term outcomes of mother-baby health and well-being during the pandemic.

Year:  2020-2022  /  Month: May /  Role: PI on sub-study /  Direct annual cost: $1,109,463 (sub-study $537,290)  /  Stockwell (PI)

CPRC Seed Grant

Columbia Population Research Center

Examination of race/ethnicity and other predictors of toddler sleep health using objective measuresThis project is a follow up on our prior CPRC Seed Grant examining sleep and race within the larger COMBO (COVID-19 Mother Baby Outcomes) study, now using actigraphy as an objective measure of sleep.

Year:  2021-2022  /  Month: July /  Role: Co-Investigator /  Donation: $20,000  /   Sania (MPI)

Pfizer

Effects of In Utero SARS-CoV-2 Exposure on Infant Growth in the COVID-19 Mother Baby Outcomes (COMBO) Cohort

Growth and body composition will be assessed in the first year of life to determine potential long-term consequences of in utero exposure to maternal SARS-CoV-2 infection.Role: Co-Investigator

Year:  2021-2022  /  Month:  September  /  Role: Co-Investigator /  Donation: $100,000  /   Fennoy (PI)

NIH/NIMH

Multiscale connectomic principles of resilience and susceptibility in mouse

This project investigates individual variability in the structural and functional connectomes associated with divergent stress response in an adult social defeat model.

Year:  2017-2022  /  Month: August /  Role: PI  /  Donation: $250,000  /  Dumitriu (PI)

CPRC Seed Grant

Columbia Population Research Center

The impact of maternal race and psychosocial stress in the context of the COVID-19 pandemic on mother and newborn sleep health. This project focuses on the specific question of sleep and race within the larger COMBO (COVID-19 Mother Baby Outcomes) study.

Year:  2020-2021  /  Month:  July  /  Role: Contact PI  /  Donation: $20,000  /   Dumitriu & Monk (MPI)

RISE Award

Columbia University

Novel telemetry for studying wild rats in the wildIn collaboration with Dr. John Kymissis from Electrical Engineering, we will build implantable, peer-to-peer enabled, rechargeable telemetry devices for rats.

Year:  2019-2021  /  Month:  June  /  Role: Contact PI /  Donation: $160,000  /  Dumitriu & Kymissis (MPI)

NIH

California national primate center

This project seeks to lay the foundation of successful synaptic aging by investigating the molecular profiles of cortical synapses from intact versus cognitively impaired monkeys

Year:  2018-2019  /  Month:  December  /  Role: PI subcontract  /  Donation: $66,688  /   Carter (PI)

NIH/NIA

Estrogen and the aging brain

This PPG investigates the relationship between endocrine status and aging with respect to reproductive physiology and cognition in both rodent and primate models.

Year:  2021-2022  /  Month: March  /  Role: Co-Investigator  /  Donation: $10,000 /   Baxter (PI)

NARSAD Young Investigator Award

Brain and Behavior Research Foundation

Role of circuit-specific cortical synaptic plasticity in driving susceptibility versus resilience to depressionThe goal of this study is to elucidate the connectomic and plasticity mechanisms that underlie distinct behavioral outcomes following stress in a mouse social defeat paradigm by looking at cFos activation patterns and dendritic spine morphology.

Year:  2015-2017  /  Month: January /  Role: PI /  Donation: $65,000  /   Dumitriu (PI)

NIH/NIMH

Live-Imaging and characterization of estrogen-induced dendritic spines

Ruth L. Kirschstein National Research Service Award to support MSTP training, including salary, tuition, supplies, travel.

Year:  2008-2012  /  Month: April /  Role: PI /  Donation: $177,624  / Dumitriu (PI)